Simultaneous Immunization against Tuberculosis
نویسندگان
چکیده
منابع مشابه
Simultaneous Immunization against Tuberculosis
BACKGROUND BCG, the only licensed vaccine against tuberculosis, provides some protection against disseminated disease in infants but has little effect on prevention of adult pulmonary disease. Newer parenteral immunization prime boost regimes may provide improved protection in experimental animal models but are unproven in man so that there remains a need for new and improved immunization strat...
متن کاملHistory of Immunization against Tuberculosis
The isolation and cultivation of the tubercle bacillus by R. Kocli gave a great impetus to the efforts to immunize susceptible animals against tuberculosis. The methods of vaccination successfully used in a certain number of bacterial infections were naturally seized upon so as to arrive at the same results in this disease. The discovery of tuberculin by Koch led people to hope that it would be...
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Objective(s): Mycobacterium tuberculosis (M. tuberculosis), an intracellular pathogen, causes 1.5 million deaths globally. Bacilli Calmette-Guérin (BCG) is commonly administered to protect people against M. tuberculosis infection; however, there are some obstacles with this first-generation vaccine. DNA vaccines, the third generation vaccines, can induce cellular immun...
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For about half a century immunization against tuberculosis has been subjected to comPrehensive scientific investigation, and during the last three decades about 300 million children have been vaccinated against the disease. An enormous amount of knowledge and practical experience has thus been accumulated, and yet immunization against tuberculosis is a matter of controversy. Widely differing vi...
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frequently be avoided if the subjects show the fixity of purpose described here; their determination to minimise the wind-chill factor (by digging a substantial snow cave) and to overcome the urge to sleep undoubtedly prevented a serious outcome for this party, which carried no specific equipment to spend a night out near the summit of Everest. CHARLES CLARKE Medical Officer, British Everest Ex...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0027477